Sometimes, the effects of drugs on sex change with time. Drugs that interfere with any stage of a person’s sexual response, including their thoughts and feelings, can affect sex.

Certain recreational drugs or substances can indeed impact sexual desire and performance. Substances like alcohol, marijuana, cocaine, and amphetamines can potentially lead to changes in libido, arousal, and the ability to achieve or maintain an erection or achieve orgasm. It's important to note that the effects can vary widely depending on the individual, the substance, the dosage, and other factors.

If you're concerned about the impact of substances on your sexual health, it's a good idea to consult with a healthcare professional.