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We get it — if you’re going to the trouble of swallowing your daily supplements, you want to know the best time of day to take it. There’s no point in spending money on extra vitamins and minerals if they're not going to get absorbed that well, or you’re just going to pee it out.
Which is why people are curious about the best time to take probiotics and vitamins — in particular vitamin D .
But you can’t get all you need through sun exposure alone (especially because we all need to be protecting ourselves from the sun's damaging rays) and you may not be getting what you need through the food you eat. That’s why it’s “very reasonable,” to take a supplement to be sure.
Vitamin D benefits
Vitamin D helps you absorb calcium, which of course helps to build and maintain strong bones. In fact, the two — calcium and vitamin D — together can help protect you from osteoporosis, a disease that weakens your skeleton and makes bones more likely to break if you should fall, adds Carol Haggans, MS, RD, a spokesperson for the NIH Office of Dietary Supplements. Your muscles also need it to do their thing, as do your nerves, which carry messages between your brain and your body. Oh, and without vitamin D, your immune system would be less adept at fighting off bacteria and viruses.
When to take vitamin D
It just plain doesn’t matter, as long as you take it with food, says Dr. Manson. Her advice: Take it when you’ll remember to take it — morning, noon or night — and take it with a meal, she says. “It is important that it be taken with food, because vitamin D is a fat-soluble vitamin,” meaning it does not dissolve in water and is absorbed with fat, so it is better if there’s a little healthy fat to mix it up with.
Sources - https://www.goodhousekeeping.com/health/a43893459/best-time-to-take-vitamin-d/